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See NeuroDeep® in action at 2 Demo Days in October

See NeuroDeep® in action at 2 Demo Days in October

Experience the developmental system of the world’s first holographic microendoscope in action in Magdeburg or Vienna.

An exciting time for DeepEn’s team. We proudly present the result of 2 years of work during 2 demo sessions at the end of October. The minimally invasive microendoscope NeuroDeep goes on tour. Busy times!

Demo #1 at 3rd Day of Intravital Microscopy – 23.10 and 24.10 in Magdeburg

This event is organized by the team “Intravital Microscopy” of German Bioimaging, an association of experts to connect practical performers of intravital microscopy and exchange techniques, methods, tips, and tricks. As such, it is very fortunate that this year, the Day of Intravital Microscopy is held at our partner institute in Magdeburg, the Leibniz Institute for Neurobiology, short LIN. Not only will two members of the DeepEn team show you the current performance of our NeuroDeep test system, but our co-founder Prof. Dr. Tomas Cizmar will also give a presentation about the the photonic technology behind it.

Demo #2 at IEEE Sensors 2023 – 30.10. in Vienna

If you are in Vienna and joining the IEEE Sensors, you can meet us for a demonstration on the 30th of October. The IEEE Sensors brings together almost 1000 researchers, engineers, and industry players for one of the most impactful gatherings with a focus on sensors and sensor systems. Optical fibres have been used for a long time as sensors, for example, to measure heat, deformation, or the concentration of chemicals. However, the possibility of using fibres for imaging should be very new to many in the community. We are looking forward to the feedback from the experts after our demonstration of our minimally invasive deep brain imaging system.

Excited for the first Demo

The functionality of the system has already been tested in different Neuroscience labs all over Europe. Now we want to demonstrate it to the critical eye of the public in order to collect even more valuable feedback. And of course, there is always excitement involved. Will the intricate optoelectronic heart of NeuroDeep work under the unpredictable and suboptimal conditions during a live demo? We are willing to try!

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Bringing Neurophotonics to Laser World

Bringing Neurophotonics to Laser World

First time as a Strat-up at Europe’s biggest Photonics Trade Show

From June 27th to June 30th, 2023, our DeepEn colleagues Sergey (CEO) and Jiri (CTO) embarked on a significant journey to attend the Laser World of Photonics conference in Munich, one of Europe’s largest and most important photonics events. Their primary objective was to showcase the innovative potential of microendoscopy in the field of neurophotonics.

For Sergey, this marked his inaugural visit to a photonics convention not as a scientist but as a business leader. The two co-founders were on a mission to present DeepEn’s vision of introducing the first commercially available microendoscope for neuroscience applications. NeuroDeep® 1.0 represents an advanced laboratory setup that utilizes state-of-the-art holographic principles to facilitate microscopic imaging through an incredibly thin fiber. This technology is designed to serve as an endoscopic probe for minimally invasive imaging of living brain tissue.

Depending on the circumstances, NeuroDeep has the capacity to enable neuroscientists to achieve high-resolution or high-speed imaging of deep brain regions. This opens up possibilities for structural and functional imaging in critical areas such as the hippocampus, amygdala, or brain stem, all without the need to extract the overlying tissue.

NeuroDeep can already reliably resolve submicrometric features, such as dendritic spines, which can be imaged using commonly used fluorescence-labelling techniques. This capability can allow researchers to better observe changes caused by neurodegenerative diseases over time. To make deep brain neuron activity visible NeuroDeep can also be used for calcium imaging techniques. In the near future, DeepEn aims to tackle what is widely considered the holy grail of neuroimaging: voltage imaging, which would enable the visualization of neuron action potentials at significantly higher frequencies.

At the Laser World of Photonics in Munich, our project received substantial interest and attention. We shared a booth with colleagues from the research association Leibniz Health Technologies, and we are immensely grateful to them for providing us with this opportunity.

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DeepEn’s in-vivo imaging technology at FENS 2022 – Meeting the brightest minds in Neuroscience.

DeepEn’s in-vivo imaging technology at FENS 2022 – Meeting the brightest minds in Neuroscience.

As a young startup with a technological background in the field of photonics and an ambition to provide helpful tools to neuroscientists, it is very important for the DeepEn Team to understand where modern brain research is moving.

And what would be a better place to get connected with the top of the field than the FENS Forum of neuroscience, the largest international neuroscience meeting in Europe? Therefore, DeepEn Team members Hana and Sergey went to Paris to connect with key-opinion-leaders in the field of brain research and catch up with partners and collaborators that were essential to get holographic endoscopy where it is today. The two used the time of the conference from 9-13 of July 2022 to connect with leading scientists and present and discuss the in-vivo imaging technology with them.

The FENS (Federation of European Neuroscience Societies) conference is renowned for gathering top-tier scientists, researchers, and industry professionals, and serves as an annual platform for knowledge exchange, breakthrough sharing, and collaboration in neuroscience. From the very start of the DeepEn research transfer project, we were sure that FENS was the place to be for us.

And we were very happy that we also had time not only to build new relations, but also strengthen existing once. Our colleagues from ISI-CAS in Brno were at FENS, as well as colleagues from LIN in Magdeburg and the University of Edinburgh. It was in Scotland where DeepEn Co-founders Tomas and Sergey first collaborated with neuroscientists to use the holographic endoscopy for bioimaging successfully. If you are interested, read more about the results of this collaboration in this paper. Meeting up again with the colleagues and brainstorming about prospective future projects gave us a lot of inspiration.

All in all, though we could not yet demonstrate the prototype of DeepEn’s first device, the NeuroDeep V1.0 Laboratory system, we could still gather information, make new contacts, and get the opinion of scientists in the different areas of neuroscience. Be sure that DeepEn will be back at FENS in the near future, then with our own holographic endoscope prototype ready to be showcased.

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